IVF and Infertility Statistics Submitted by Infertility Solutions P.C.

IVF Pregnancy Data and Statistics - Infertility Solutions P.C.

(data compiled 1/8/2008)

We participate in national reporting of IVF data as administered by the Center for Disease Control (CDC) and the American Society of Reproductive Medicine's Society for Advanced Reproductive Technologies (SART). This nationally collected database can be reviewed at www.cdc.gov/art/art2005. One of the shortcomings of this data is that it may be up to two years old. This is because it is reported on an annual basis and the data has to wait for all babies to be born who were conceived in the prior calendar year. Much can change in a program in that time period including personnel, procedures and equipment.

Our laboratory was completely redesigned to take advantage of newly available state-of-the-art technologies at the beginning of 2003. We have also changed our approach to laboratory personnel to try to capture the advantages of both small and large programs by supplementing our embryology staff with ongoing outside embryologists. For example, Dr. Lynette Scott, Joe Sokoloski, and Dr. Frank Barnes have served in this capacity.

The availability of the internet makes it possible to present more up-to-date information about our program. This information can be used with the CDC/SART data to make an informed decision about program selection. We present ongoing pregnancy results with information about the patients but with identifying details removed.

Summary data is expressed in terms of pregnancy rate per IVF embryo transfer. Most of the time embryos are produced during an IVF cycle, but the problem is to get them to implant and become babies. Three types pregnancies are highlighted- biochemical (positive pregnancy test), clinical (tissue or ultrasound evidence of pregnancy including tubal pregnancies), and ongoing/delivered (the pregnancies delivered or with a high probability of delivering). These three types of pregnancy rates provide diffent kinds of information. The ongoing/delivered pregnancy rate provides the most useful prognostic information for patients considering a program. The clinical pregnancy rate is more a reflection of the laboratory competence of the program since many pregnancy losses of clinical pregnancies reflect patient characteristics (e.g., ectopic pregnancy). Biochemical pregnancy rate reflect in part the efficacy of the embryo transfer procedure aas well as chomomsomal abnomality of the embryos transferred. The summary data for women under age 35 is emphasized, because less patient selection takes place in this age category. Our program does not reject informed patients on the basis of age or decreased ovarian reserve (elevated FSH levels). This may adversely effect our pregnancy rates compared to programs which do select patients, but we have had many wonderful pregnancies in patients rejected by other programs. In fact, SART requires the following statement when quoting program statistics: "A comparison of clinic success rates may not be meaningful because patient medical characteristics and treatment approaches may vary from clinic to clinic."

Time period: Embryo tranfer between January 1, 2007 through December 31, 2007

Age.................Problem.............................Outcome

24...........................PCO..........................................clinical pregnancy

25...........................PCO..........................................ongoing pregnancy

26...........................PCO..........................................biochemical pregnancy

26...........................PCO..........................................clinical pregnancy

26...........................male factor.................................ongoing pregnancy

27...........................PCO...........................................biochemical pregnancy

27............................Endometriosis and male

27............................PCO...........................................biochemical pregnancy

27............................Other..........................................ongoing pregnancy

28............................Male factor.................................ongoing pregnancy

29...........................Endometriosis and pelvic factor

29...........................PCO............................................ongoing pregnancy

29...........................PCO and male factor

30...........................Male factor...................................ongoing pregnancy

30............................Unexplained................................ongoing pregnancy

30............................Unexplained

30............................Tubal factor...............................ongoing pregnancy

30............................Tubal factor

30............................Endometriosis and PCO............ongoing pregnancy

30............................Other

31...........................Unexplained..............................ongoing pregnancy

32............................PCO.........................................ongoing pregnancy

32...........................Tubal factor...............................ongoing pregnancy

32............................Uterine factor............................ongoing pregnancy

33............................PCO and tubal factor

33............................Tubal factor...............................clinical pregnancy

33............................Unexplained

33............................PCO

33............................PCO and male factor

33............................Male factor..................................biochemical pregnancy

33............................Male factor

33............................Male factor..................................biochemical pregnancy

33............................PCO

34............................Tubal factor.................................ongoing pregnancy

34............................PCO and tubal factor

34............................Endometriosis.............................ongoing pregnancy

34............................PCO and tubal factor...................biochemical pregnancy

34............................PCO............................................ongoing pregnancy

34............................PCO and tubal factor

34............................Male and uterine factor

35............................Male and tubal factor...................ongoing pregnancy

35............................PCO and male factor

35............................Male factor and PCO..................ongoing pregnancy

35............................Ovarian reserve...........................ongoing pregnancy

35............................PCO and male factor

35............................Male factor and ovarian reserve....ongoing pregnancy

36............................Tubal factor

36............................Ovarian failure

36............................Male factor...................................ongoing pregnancy

37............................Male factor

37............................Tubal factor

37............................Tubal factor.................................ongoing pregnancy

37............................Unexplained

37............................Tubal factor

37...........................Ovarian reserve

38...........................Unexplained

38...........................Other

38...........................Ovarian reserve............................biochemical pregnancy

39...........................Ovarian reserve and male factor

39...........................Ovarian reserve............................biochemical pregnancy

39............................PCO and tubal factor

40............................Endometriosis and ovarian reserve

40............................Ovarian reserve

40............................Other...........................................clinical pregnancy

41............................Male factor

41............................Male factor and ovarian reserve...biochemical pregnancy

43............................Male factor and ovarian reserve

43............................Ovarian reserve............................biochemical pregnancy

44............................Ovarian reserve

45............................Ovarian reserve

45............................Ovarian reserve............................biochemical pregnancy

45............................Ovarian reserve............................clinical pregnancy

47............................Male factor and ovarian reserve

47............................Male factor and ovarian reserve.....clinical pregnancy

Summary data for fresh IVF (patients under age 35) for the year 2007*:

Biochemical pregnancies/IVF transfers- 25/42 or 59.5%

Clinical pregnancies/IVF transfers- 20/42 or 47.6%

Ongoing or delivered pregnancies/IVF transfers- 16/42 or 38.1%

Summary data for fresh IVF (patients under age 43) for the year 2007*:

Clinical pregnancies/IVF transfers- 27/70 or 38.6%

Ongoing or delivered pregnancies/IVF transfers- 23/70 or 32.9%

Summary data for fresh IVF (patients under age 35) for the year 2006 *:

Clinical pregnancies/IVF transfers- 14/32 or 43.8%

Delivered pregnancies/IVF transfers- 11/32 or 34.4%

Summary data for fresh IVF (patients under age 43) for the year 2006 *:

Clinical pregnancies/IVF transfers- 28/74 or 37.8%

Delivered pregnancies/IVF transfers- 21/74 or 28.3%

Summary data for fresh IVF (patients under age 35) for the year 2005 * +:

Clinical pregnancies/IVF transfers- 22/41 or 53.7%

Delivered pregnancies/IVF transfers- 13/41 or 31.7%

Summary data for fresh IVF (patients under age 43) for the year 2005 * +:

Clinical pregnancies/IVF transfers- 38/75 or 50.7%

Delivered pregnancies/IVF transfers- 24/75 or 32%

*If using donor eggs, the age of the donor is used.

+2005 data is for 13 months

Summary data for fresh IVF (patients under age 35) for the years 2003 through 2006**:

Clinical pregnancies/IVF transfers- 64/133 or 48.1%

Delivered pregnancies/IVF transfers- 46/133 or 34.6%

**Data in the above format is available by request

2005 patient data

2006 patient data