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We participate in national reporting of IVF data as administered by the Center for Disease Control (CDC) and the American Society of Reproductive Medicine's Society for Advanced Reproductive Technologies (SART). This nationally collected database can be reviewed at www.cdc.gov/art. One of the shortcomings of this data is that it may be up to two years old. This is because it is reported on an annual basis and the data has to wait for all babies to be born who were conceived in the prior calendar year. Much can change in a program in that time period including personnel, procedures and equipment.
Our laboratory was completely redesigned to take advantage of newly available state-of-the-art technologies at the beginning of 2003. We have also changed our approach to laboratory personnel to try to capture the advantages of both small and large programs by supplementing our embryology staff with ongoing outside embryologists. For example, Dr. Lynette Scott and Joe Sokoloski have served in this capacity.
The availability of the internet makes it possible to present more up-to-date information about our program. This information can be used with the CDC/SART data to make an informed decision about program selection. We present ongoing pregnancy results with information about the patients but with identifying details removed.
Summary data is expressed in terms of pregnancy rate per IVF embryo transfer. Most of the time embryos are produced during an IVF cycle, but the problem is to get them to implant and become babies. Three types pregnancies are highlighted- biochemical (positive pregnancy test), clinical (tissue or ultrasound evidence of pregnancy including tubal pregnancies), and ongoing/delivered (the pregnancies delivered or with a high probability of delivering). These three types of pregnancy rates provide diffent kinds of information. The ongoing/delivered pregnancy rate provides the most useful prognostic information for patients considering a program. The clinical pregnancy rate is more a reflection of the laboratory competence of the program since many pregnancy losses of clinical pregnancies reflect patient characteristics (e.g., ectopic pregnancy). Biochemical pregnancy rate reflect in part the efficacy of the embryo transfer procedure aas well as chomomsomal abnomality of the embryos transferred. The summary data for women under age 35 is emphasized, because less patient selection takes place in this age category. Our program does not reject informed patients on the basis of age or decreased ovarian reserve (elevated FSH levels). This may adversely effect our pregnancy rates compared to programs which do select patients, but we have had many wonderful pregnancies in patients rejected by other programs.
Time period: Embryo tranfer between February 1, 2006 through December 31, 2006
Age.................Problem.............................Outcome
26.......................PCO and male factor.....................clinical pregnancy
27.......................endometriosis and tubal.................biochemical pregnancy
28.......................male
28.......................male
28.......................male..............................................biochemical pregnancy
29.......................unexplained...................................ongoing pregnancy
29.......................endometriosis and PCO................biochemical pregnancy
29.......................endometriosis and PCO................ongoing pregnancy
29.......................endometriosis................................biochemical pregnancy
30.......................PCO.............................................ongoing pregnancy
30.......................PCO
30.......................PCO
30.......................decreased ovarian reserve..............ongoing pregnancy
31.......................PCO
31.......................PCO...............................................clinical pregnancy
31.......................endometriosis and PCO................ongoing pregnancy
31.......................endometriosis and tubal
31.......................ovarian reserve..............................ongoing pregnancy
32.......................ovarian reserve
32.......................PCO...............................................ongoing pregnancy
32.......................PCO and male factor
32.......................unexplained....................................biochemical pregnancy
33.......................PCO
33.......................PCO..............................................ongoing pregnancy
33.......................ovarian reserve
33.......................ovarian reserve..............................ongoing pregnancy
34.......................male factor and PCO.....................clinical pregnancy
34.......................unexplained
34.......................unexplained...................................ongoing pregnancy
34........................male factor...................................ongoing pregnancy
34.......................male factor and PCO
35.......................PCO and tubal
35.......................PCO and tubal
35.......................PCO and tubal
35.......................PCO..............................................biochemical pregnancy
35........................male factor...................................ongoing pregnancy
36.......................tubal factor
36.......................endometriosis, tubal, and PCO
36.......................PCO..............................................ongoing pregnancy
36.......................unexplained....................................clinical pregnancy
36.......................tubal and uterine factor
36.......................tubal and uterine factor....................ongoing pregnancy
36.......................male factor and PCO.......................ongoing pregnancy
37.......................unexplained
37.......................PCO................................................biochemical pregnancy
37.......................tubal and male factor.......................clinical pregnancy
37.......................male factor
37.......................male factor and ovarian reserve.......ongoing pregnancy
37.......................PCO, tubal and male factor
37........................male and tubal factor
38........................tubal and decreased ovarian reserve
38........................endometriosis and tubal factor
38........................decreased ovarian reserve................biochemical pregnancy
38.......................PCO
38.......................male and tubal factor
38.......................male and tubal factor.........................ongoing pregnancy
38........................male factor
39.......................PCO and tubal factor.........................ongoing pregnancy
39.......................ovarian reserve
39.......................ovarian reserve...................................biochemical pregnancy
39.......................ovarian reserve...................................biochemical pregnancy
39.......................ovarian reserve...................................biochemical pregnancy
39.......................unexplained.......................................ongoing pregnancy
39.......................male factor.........................................ongoing pregnancy
39.......................tubal factor
39.......................male factor........................................ongoing pregnancy
39.......................ovarian reserve and tubal factor.........ongoing pregnancy
39........................endometriosis and tubal factor
40.......................ovarian reserve
40.......................male factor........................................clinical pregnancy
41.......................male factor
41.......................male factor and ovarian reserve
42.......................tubal....................................................clinical pregancy
43.......................unexplained
44.......................decreased ovarian reserve
46.......................male factor and ovarian reserve
Summary data for fresh IVF (patients under age 35) for the year 2006 to date*:
Biochemical pregnancies/IVF transfers- 13/19 or 68.4%
Clinical pregnancies/IVF transfers- 10/19 or 52.6%
Ongoing or delivered pregnancies/IVF transfers- 8/19 or 42.1%
Summary data for fresh IVF (patients under age 43) for the year 2006 to date*:
Clinical pregnancies/IVF transfers- 18/42 or 42.9%
Ongoing or delivered pregnancies/IVF transfers- 14/42 or 33.3%
Summary data for fresh IVF (patients under age 35) for the year 2005 * +:
Biochemical pregnancies/IVF transfers- 30/41 or 73.2%
Clinical pregnancies/IVF transfers- 22/41 or 53.7%
Ongoing or delivered pregnancies/IVF transfers- 13/41 or 31.7%
Summary data for fresh IVF (patients under age 43) for the year 2005 * +:
Clinical pregnancies/IVF transfers- 38/75 or 50.7%
Ongoing or delivered pregnancies/IVF transfers- 24/75 or 32%
*If using donor eggs, the age of the donor is used.
+2005 data is for 13 months
Summary data for fresh IVF (patients under age 35) for the years 2003 through 2005**:
Clinical pregnancies/IVF transfers- 49.5%
Delivered pregnancies/IVF transfers- 34.7%
**Data in the above format is available by request
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